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Glomerular Filtration Rate, Estimated
0020725
Ordering Recommendation
Mnemonic
GFRE
Methodology
Quantitative Enzymatic
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plasma separator tube or serum separator tube. Also acceptable: Lavender (EDTA). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Specimens obtained through catheters used to infuse hyperalimentation fluid. Specimens collected with potassium oxalate/sodium fluoride or sodium citrate. 
Remarks
Patient age and sex are required for calculation. 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months 
Reference Interval
Effective August 20, 2018
Calculated GFR - >= 60 mL/min / 1.73 square meters
Creatinine
Age
Male
Female
0-30 days0.50-1.20 mg/dL0.50-0.90 mg/dL
31-364 days0.40-0.70 mg/dL0.40-0.60 mg/dL
1-3 years0.40-0.70 mg/dL0.40-0.70 mg/dL
4-6 years0.50-0.80 mg/dL0.50-0.80 mg/dL
7-9 years0.30-0.60 mg/dL0.30-0.70 mg/dL
10-11 years0.30-0.70 mg/dL0.40-0.80 mg/dL
12-13 years0.40-0.80 mg/dL0.40-0.80 mg/dL
14-15 years0.40-1.10 mg/dL0.30-0.90 mg/dL
16-18 years0.60-1.20 mg/dL0.50-1.00 mg/dL
19 years and older0.40-1.20 mg/dL0.40-1.20 mg/dL

Interpretive Data
The CKD-EPI equation for non-African American individuals is used to calculate the estimated glomerular filtration rate (GFR). To estimate the GFR for African Americans, multiply the provided GFR result by 1.16.

The CKD-EPI equation is validated in individuals 18 years of age and older. It is less accurate in patients with extremes of muscle mass, restriction of dietary protein, ingestion of creatine, extra-renal metabolism of creatinine, or treatment with medications that affect renal tubular creatinine secretion.

GFR Categories in Chronic Kidney Disease (CKD)
GFR Category
GFR (mL/min/1.73 square meters)
Interpretation
G190 or greaterNormal or high*
G260-89Mild decrease*
G3a45-59Mild to moderate decrease
G3b30-44Moderate to severe decrease
G415-29Severe decrease
G514 or lessKidney failure
*In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD (Kidney Int Suppl 2013;3:1-150)

Note
Hotline History
View Hotline History
Components
Component Test Code*Component Chart NameLOINC
0020025Creatinine, Serum or Plasma2160-0
0026634Calculated GFR62238-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Calculated Glomerular Filtration Rate
  • cGFR
  • eGFR
  • Estimated Glomerular Filtration Rate