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Ordering Recommendation:   Use only to provide evidence of vaccination or prior infection by measles, mumps, rubella and varicella-zoster viruses.
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Ordering Recommendation:   Preferred CSF test for the workup of suspected multiple sclerosis. Detects IgG oligoclonal bands in CSF and calculates the CSF IgG index.
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Ordering Recommendation:   Sensitive screening test for multiple sclerosis. Preferred test is Oligoclonal Band Profile (0080440).
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Ordering Recommendation:   Pretherapeutic identification of individuals who may require higher or lower doses of opioid drugs to achieve adequate pain control or have a better response to naltrexone for the treatment of alcohol and/or opioid dependency.
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Ordering Recommendation:   For routine biochemical screening, refer to Organic Acids, Urine (0098389).
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Ordering Recommendation:   Molecular (DNA) test to confirm a diagnosis of ornithine transcarbamylase (OTC) deficiency performed when Ornithine Transcarbamylase Deficiency (OTC) Sequencing (2004901) does not identify the causative mutation. Carrier testing for individuals who have a family history of a deletion or duplication in the OTC gene.
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Ordering Recommendation:   Molecular (DNA) test to confirm a diagnosis of ornithine transcarbamylase (OTC) deficiency following clinical and biochemical presentation. To diagnose or rule out OTC deficiency, refer to Amino Acids Quantitative by LC-MS/MS, Plasma (2009389), Organic Acids, Urine (0098389), and Orotic Acid and Orotidine, Urine (0092458).
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Ordering Recommendation:   Preferred molecular (DNA) test to confirm a diagnosis of ornithine transcarbamylase (OTC) deficiency following clinical and biochemical presentation. To diagnose or rule out OTC deficiency, refer to Amino Acids Quantitative by LC-MS/MS, Plasma (2009389), Organic Acids, Urine (0098389), and Orotic Acid and Orotidine, Urine (0092458).
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Ordering Recommendation:   For proper evaluation of patients with a suspected urea cycle disorder, order Amino Acids Quantitative by LC-MS/MS, Plasma (2009389), Amino Acids Quantitative by LC-MS/MS, Urine (2009419), and Organic Acids, Urine (0098389) concurrently with Orotic Acid testing.
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Ordering Recommendation:   If parasite infection is suspected as cause of persistent diarrhea (> 14 days), specific pathogen testing is recommended (refer to Gastrointestinal Parasite Panel by PCR (2011150); Giardia Antigen by EIA (0060048); Entamoeba histolytica Antigen, EIA (0058001); or Cryptosporidium Antigen by EIA (0060045)). Do not order for patients who develop diarrhea during a prolonged hospitalization.
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Ordering Recommendation:   A simultaneously drawn control specimen must be submitted to allow for meaningful interpretation. Use this test to screen for hemoglobin variants with high- and low-oxygen affinities in individuals with isolated polycythemia who lack a JAK2 gene mutation and do not exhibit other clinical symptoms suggestive of polycythemia vera (eg, leukocytosis, thrombocytosis, or splenomegaly) or in cyanotic individuals.