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156 results found.

1.
Ordering Recommendation:  

Aid in the diagnosis of invasive/disseminated fungal infections (eg, P. jirovecii, Aspergillus, or Candida).

2.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

3.
Ordering Recommendation:  

Used primarily to monitor response to rituximab therapy.

4.
Ordering Recommendation:  

Aid in diagnosis and monitoring of B-cell lymphoproliferative disorders and in differentiating malignant from reactive lymphoid proliferations.

5.
Ordering Recommendation:  

Assess B-cell subsets of immunodeficiencies. Supports the diagnosis of common variable immune deficiency (CVID) and may help predict the clinical phenotype. Assess B-cell reconstitution after bone marrow or hematopoietic stem cell transplantation. Not recommended for rituximab monitoring; refer to 0092099 B-Cell CD20 Expression.

6.
Ordering Recommendation:  

Aids in diagnosis, prognosis, and management of acute and chronic heart failure.

7.
Ordering Recommendation:  

Useful if Giemsa stain is negative but high suspicion of babesiosis exists. Will not detect B. duncani or strain MO-1.

8.
Ordering Recommendation:  

Refer to Babesia microti Antibodies, IgG and IgM by IFA (0093048) panel, which includes IgG and IgM by IFA.

9.
Ordering Recommendation:  

Refer to Babesia microti Antibodies, IgG and IgM by IFA (0093048) panel, which includes IgG and IgM by IFA.

10.
Ordering Recommendation:  

First-line test for diagnosing acute babesiosis. This PCR test detects nucleic acid from B. microti and detects but does not differentiate between B. duncaniB. divergens, strain MO-1, and strain EU-1. Blood smears are also appropriate for diagnosing and monitoring babesiosis disease; refer to Parasites Smear (Giemsa Stain), Blood (0049025).

11.
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13.
Ordering Recommendation:  

Gold-standard testing for epidemiological investigation of infectious outbreaks.

14.
Ordering Recommendation:  

• Use for infant drug testing when only barbiturate exposure is of clinical interest or when quantity of meconium available for testing is very small (eg, <1 g).
• Preferred test is the meconium panel that reflexes to confirmation and quantitation (refer to 0092516).

15.
Ordering Recommendation:  

Optimize drug therapy and monitor patient adherence. Useful for ruling out barbiturate exposure. For follow-up testing of a presumptive result, Barbiturates, Urine Quantitative (2012213) is preferred.

16.
Ordering Recommendation:  

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out barbiturate exposure. For follow-up testing of a presumptive result, Barbiturates, Urine Quantitative (2012213) is preferred.

17.
Ordering Recommendation:  

Preferred test to follow-up presumptive results. For general screening, Barbiturates Urine Screen with Reflex to Quantitation (2012211) is preferred.

18.
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20.
Ordering Recommendation:  

May confirm a current or past exposure to B. henselae or B. quintana in patient with typical signs and symptoms and a compatible exposure history.

21.
Ordering Recommendation:  

May assist in diagnosing cat scratch disease in patient with typical signs and symptoms and a compatible exposure history.

22.
Ordering Recommendation:  

May assist in confirming a current or past Bartonella henselae infection.

23.
Ordering Recommendation:  

May assist in confirming an early or recent Bartonella henselae infection.

24.
Ordering Recommendation:  

May assist in confirming suspected Trench fever in patient with typical signs and symptoms and compatible exposure history.

25.
Ordering Recommendation:  

May assist in confirming suspected Trench fever in patient with typical signs and symptoms and compatible exposure history.

26.
Ordering Recommendation:  

May assist in confirming suspected Trench fever in patient with typical signs and symptoms and compatible exposure history.

27.
Ordering Recommendation:  

Detect Bartonella species in blood, CSF, or tissue.

28.
Ordering Recommendation:  

Detect Bartonella species in whole blood.

29.
30.
Ordering Recommendation:  

May be useful in the assessment of acute exposure to bath salts. For assessment several days post-exposure, Bath Salts Panel, Urine (2008650) is preferred.

31.
Ordering Recommendation:  

May be useful in the assessment of exposure to bath salts up to several days post-exposure. For the assessment of acute exposure, Bath Salts Panel, Serum or Plasma (2011411) may be useful.

32.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

33.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

34.
Ordering Recommendation:  

Sensitive method for detecting MYC rearrangement in FFPE.

35.
Ordering Recommendation:  

Order only for patients with an established diagnosis of a BCR-ABL1 positive leukemia. This test is used to determine if a mutation is present that would interfere with response to TKI therapy in Philadelphia chromosome positive (Ph+) lymphoblastic leukemia or chronic myelogenous leukemia (CML). The test detects all common mutations, including T315I. For initial BCR-ABL1 testing, refer to the reflex test (2005010).

36.
Ordering Recommendation:  

This quantitative test is appropriate for diagnosis and therapeutic monitoring for CML or ALL. The BCR-ABL1 major (p210) fusion forms are present in almost all cases of CML and in a small subset of cases of ALL.

37.
Ordering Recommendation:  

Order in cases of Philadelphia chromosome positive (Ph+) lymphoblastic leukemia to quantify the BCR-ABL1 p190 fusion form. For CML, use BCR-ABL1, Major (p210), Quantitative, (2005017).

38.
Ordering Recommendation:  

For use in detecting the presence of a BCR-ABL1 fusion, for determining breakpoint status, and for baseline quantitation.

39.
Ordering Recommendation:  

Aids in the workup of plasma cell dyscrasia. Use to detect and quantify urinary free light chains (Bence Jones protein).

40.
41.
42.
Ordering Recommendation:  

Optimize drug therapy and monitor patient adherence.

43.
Ordering Recommendation:  

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out benzodiazepine exposure. For follow-up testing of a presumptive result, Benzodiazepines, Urine Quantitative (2008291) is preferred.

44.
Ordering Recommendation:  

Preferred test to follow-up presumptive results. For general screening, Benzodiazepines Urine Screen with Reflex to Quantitation (2012225) is preferred.

45.
46.
Ordering Recommendation:  

Recommended test for identifying beryllium sensitization and chronic beryllium disease (CBD). Use in asymptomatic individuals with chronic exposure to beryllium or in symptomatic individuals with a history of beryllium exposure.

47.
Ordering Recommendation:  

Confirm an exposure to beryllium but NOT useful indicator for determining time since exposure or the extent of an exposure. Refer to Beryllium Lymphocyte Proliferation Test (2011052) for a more reliable indicator of beryllium sensitization and/or Chronic Beryllium Disease (CBD).

48.
Ordering Recommendation:  

This is a second tier test and REQUIRES PERMISSION from ARUP's Genetic Counselor (800-242-2787, x2141) before ordering. Preferred initial test is the combined sequencing and deletion/duplication test.

49.
Ordering Recommendation:  

Molecular confirmation of a suspected structural hemoglobinopathy or beta thalassemia.

50.
Ordering Recommendation:  

Confirm suspected HbS, HbC, and HbE variants.

51.
Ordering Recommendation:  

Genetic test on fetal specimens for prenatal detection of HbS, HbC, and HbE variants.

52.
Ordering Recommendation:  

Preferred test for molecular confirmation of beta thalassemia or a hemoglobinopathy involving the beta-globin gene.

53.
Ordering Recommendation:  

Confirmatory genetic test on fetal samples for the prenatal detection of structural hemoglobinopathies and beta thalassemia.

54.
Ordering Recommendation:  

Acceptable initial test when antiphospholipid syndrome (APS) is strongly suspected. Order with lupus anticoagulant (LA) (0030181) and anticardiolipin (aCL) IgG and IgM (0099344) assays. May also be useful in estimating risk of thrombosis and/or pregnancy-related morbidity in patients with SLE.

55.
Ordering Recommendation:  

Preferred panel is 0050321 when antiphospholipid syndrome (APS) is strongly suspected.

56.
Ordering Recommendation:  

Preferred second-line testing for patients considered seronegative antiphospholipid syndrome (APS). Order incrementally or concurrently with other non-criteria antiphospholipid antibody tests. May also be useful in estimating risk of thrombosis and/or pregnancy-related morbidity in patients with SLE.

57.
58.
Ordering Recommendation:  

Use for risk stratification and staging of multiple myeloma, Waldenstrom macroglobulinemia, and other lymphoproliferative disorders. Aids in differentiating glomerular and tubular renal disease.

59.
Ordering Recommendation:  

Aids in diagnosis of CSF leak.

60.
61.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

62.
63.
64.
65.
66.
67.
Ordering Recommendation:  

• Aid in evaluation of hyperinsulinemic hypoglycemia.
• Aid in assessment of the etiology of anion gap acidosis.
• Screen for suspected mitochondrial disorders.

68.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

69.
70.
Ordering Recommendation:  

Do not use to diagnose liver dysfunction. Use to screen for inborn errors of bile acid metabolism or monitor bile acid therapy.

71.
Ordering Recommendation:  

Use to detect hepatobiliary dysfunction. Do not order to detect inborn errors of bile acid metabolism. May aid in diagnosis of intrahepatic cholestasis of pregnancy.

72.
Ordering Recommendation:  

Useful as an indicator of in vivo breakdown of hemoglobin to differentiate cerebral hemorrhage from a traumatic tap.

73.
74.
75.
Ordering Recommendation:  

Refer to aruplab.com/bodyfluids for clinical indications and interpretive information.

76.
77.
Ordering Recommendation:  

Molecular (DNA) test to confirm a diagnosis of biotinidase (BTD) deficiency when biotinidase enzymatic activity is low. Carrier testing for individuals with a family history of BTD deficiency when familial mutations are included in the 5 mutation panel. To diagnose or rule out BTD deficiency, refer to Biotinidase, Serum (with Paired Normal Control) (0093362).

78.
Ordering Recommendation:  

Molecular (DNA) test to confirm a diagnosis of biotinidase (BTD) deficiency when biotinidase enzymatic activity is low. To diagnose or rule out BTD deficiency, refer to Biotinidase, Serum (with Paired Normal Control) (0093362).

79.
Ordering Recommendation:  

Biotinidase enzyme test. Initial test to diagnose or rule out biotinidase deficiency.

80.
Ordering Recommendation:  

May be useful in the assessment of acute or chronic exposure.

81.
Ordering Recommendation:  

Detect and quantify BK virus in blood or urine.

82.
Ordering Recommendation:  

Detect and quantify BK virus in blood.

83.
Ordering Recommendation:  

Detect and quantify BK virus in urine.

84.
Ordering Recommendation:  

This test is indicated for use as an aid in the management of bladder cancer patients in conjunction with cystoscopy. Qualitative assay detects bladder tumor associated antigen in urine of persons diagnosed with bladder cancer.

85.
Ordering Recommendation:  

Recommended test if serology is used to aid in the diagnosis of blastomycosis.

86.
Ordering Recommendation:  

Titers may aid in monitoring blastomycosis and treatment response.

87.
Ordering Recommendation:  

Not recommended as a stand-alone test. Refer to the combined complement fixation and immunodiffusion test (0050626).

88.
89.
Ordering Recommendation:  

Rapid test for identifying B. dermatitidis (yeast or mold form) from a pure isolate.

90.
Ordering Recommendation:  

Detect presence of bacteria in blood.

91.
Ordering Recommendation:  

Order to culture acid-fast bacteria from blood or bone marrow specimens.

92.
Ordering Recommendation:  

Order to culture acid-fast bacteria and fungi from blood or bone marrow specimens.

93.
Ordering Recommendation:  

Gold standard test to diagnose fungi as agent of infection in blood.

94.
95.
Ordering Recommendation:  

Carrier screening or diagnostic testing for Bloom syndrome for individuals of Ashkenazi Jewish descent.

96.
Ordering Recommendation:  

Identify bacteria in normally sterile body fluids. May assist in differentiating gout from septic arthritis. Anaerobe culture is recommended for body fluids, tissue, and deep wound/surgical cultures. Refer to Anaerobe Culture and Gram Stain (0060143).

97.
Ordering Recommendation:  

Identify bacteria in bone specimens.

98.
Ordering Recommendation:  

Identify bacteria in bone marrow.

99.
Ordering Recommendation:  

Preferred test for confirmation of hereditary bone marrow failure.

100.
101.
Ordering Recommendation:  

CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117). However, if serology is used to assess late-stage pertussis (>4 weeks), this is the recommended test.

102.
Ordering Recommendation:  

If serology is used to assess late-stage pertussis (>4 weeks), the recommended test is Bordetella pertussis Antibodies, IgA and IgG by ELISA with Reflex to Immunoblot (2001774). CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

103.
Ordering Recommendation:  

If serology is used to assess late-stage pertussis (>4 weeks), the recommended test is Bordetella pertussis Antibodies, IgA and IgG by ELISA with Reflex to Immunoblot (2001774). CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

104.
Ordering Recommendation:  

If serology is used to assess late-stage pertussis, the recommended test is Bordetella pertussis Antibodies, IgA and IgG by ELISA with Reflex to Immunoblot (2001774). CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

105.
Ordering Recommendation:  

Not a stand-alone test. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117). If serology is used to assess late-stage pertussis, the recommended test is Bordetella pertussis Antibodies, IgA and IgG by ELISA with Reflex to Immunoblot (2001774).

106.
Ordering Recommendation:  

In most cases, serology testing is not recommended for the diagnosis of active pertussis infection. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

107.
Ordering Recommendation:  

May be used as evidence of vaccination or past infection; test does not determine immunity to B. pertussis. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117). In most cases, serology testing is not recommended for the diagnosis of active pertussis infection.

108.
Ordering Recommendation:  

May be used as evidence of vaccination or past infection; test does not determine immunity to B. pertussis. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117). If serology is used to assess late-stage pertussis, the recommended test is Bordetella pertussis Antibodies, IgA and IgG by ELISA with reflex to immunoblot (2001774).

109.
Ordering Recommendation:  

Evaluation of IgM pertussis antibodies has little clinical utility. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

110.
Ordering Recommendation:  

Evaluation of IgM pertussis antibodies has little clinical utility. CDC-recommended first-line tests for pertussis are PCR (0065080) and/or culture (0060117).

111.
Ordering Recommendation:  

CDC-recommended test for the diagnosis of pertussis.

112.
Ordering Recommendation:  

CDC-recommended test for the diagnosis of pertussis. Consider concurrent testing with B. pertussis by PCR (0065080).

113.
Ordering Recommendation:  

CDC-recommended test for the diagnosis of pertussis.

114.
115.
Ordering Recommendation:  

Preferred CSF reflex panel for workup of suspected neuroborreliosis.

116.
Ordering Recommendation:  

Do not order in the absence of a positive/equivocal ELISA screening test. IgM immunoblot is not useful after the first 4 weeks of clinical symptoms.

117.
Ordering Recommendation:  

Use in conjunction with positive serologic testing for the workup of suspected acute Lyme neuroborreliosis. Do not order in the absence of clinical symptoms.

118.
Ordering Recommendation:  

First-line serologic screening test for suspected Lyme disease. Positive or equivocal results must be confirmed by immunoblot.

119.
Ordering Recommendation:  

Preferred reflex test to detect Lyme disease in individuals with ≤4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by immunoblot.

120.
Ordering Recommendation:  

Use in conjunction with positive serologic testing for the workup of suspected acute Lyme neuroborreliosis. Do not order in the absence of clinical symptoms.

121.
Ordering Recommendation:  

Do not order in the absence of a positive/equivocal ELISA screening test. During first 4 weeks of clinical symptoms, order concurrent IgM immunoblot.

122.
Ordering Recommendation:  

Use in conjunction with positive serologic testing for the workup of suspected acute Lyme neuroborreliosis. Do not order in the absence of clinical symptoms.

123.
Ordering Recommendation:  

Do not order in the absence of a positive/equivocal ELISA screening test. Useful only when ordered during first 4 weeks of clinical symptoms and concurrently with IgG immunoblot.

124.
Ordering Recommendation:  

Use in conjunction with serologic testing for the workup of suspected acute Lyme neuroborreliosis. Do not order in the absence of clinical symptoms.

125.
Ordering Recommendation:  

First-line serologic screening test for suspected Lyme disease. Positive or equivocal results must be confirmed by immunoblot.

126.
Ordering Recommendation:  

Use in conjunction with positive serologic testing for the workup of suspected acute Lyme neuroborreliosis. Do not order in the absence of clinical symptoms.

127.
Ordering Recommendation:  

Preferred reflex test to detect Lyme disease in individuals with ≤4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by immunoblot.

128.
Ordering Recommendation:  

Preferred reflex test to detect Lyme disease in individuals with >4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by immunoblot.

129.
Ordering Recommendation:  

Preferred reflex test to detect Lyme disease in individuals with >4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by immunoblot.

130.
Ordering Recommendation:  

Use for diagnostic workup of suspected tick-borne relapsing fever.

131.
Ordering Recommendation:  

Not a first-line test for Lyme disease. May be useful if strong suspicion of Lyme disease persists in spite of persistent negative serologic testing.

132.
133.
Ordering Recommendation:  

Use to detect activating BRAF mutations at codon 600, which can indicate responsiveness to BRAF inhibitors in melanomas or resistance to anti-EGFR therapy in colorectal cancer. May be useful in assessing prognosis of certain thyroid cancers. This test is also used within the Lynch syndrome reflex testing pathway (for colorectal cancer specimens only).

134.
Ordering Recommendation:  

Recommended reflex test for differentiating between Lynch syndrome and sporadic colorectal cancer in tumors showing loss of MLH1. If no BRAF mutation is detected, MLH1 promoter methylation is evaluated.

135.
Ordering Recommendation:  

Determine BRAF V600E mutation status in patients with solid tumors to select candidates for targeted therapy with kinase inhibitors (BRAF and/or MEK). Monitor response to therapy and disease progression in patients carrying BRAF V600E mutation.

136.
Ordering Recommendation:  

Confirm a diagnosis of hairy cell leukemia (HCL) and monitor tumor burden.

137.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

138.
Ordering Recommendation:  

Preferred first-tier genetic test for confirmation of hereditary breast and ovarian cancer (HBOC) syndrome.

139.
Ordering Recommendation:  

This is a second tier test and REQUIRES PERMISSION from ARUP's Genetic Counselor (800-242-2787, x2141) before ordering. Preferred initial test is the sequencing and deletion/duplication test.

140.
Ordering Recommendation:  

To determine if there is a heritable predisposition for breast or ovarian cancer in adults with any of the following:
• Breast cancer diagnosed at age 50 or younger
• Ovarian cancer
• Multiple primary breast cancers either in the same breast or opposite breast
• Both breast and ovarian cancer
• Male breast cancer
• Triple-negative (estrogen receptor negative, progesterone receptor negative, and HER2/neu [human epidermal growth factor receptor 2] negative) breast cancer
• Pancreatic cancer with breast or ovarian cancer in the same individual or on the same side of the family
• Ashkenazi Jewish ancestry
• Two or more relatives with breast cancer, one under age 50
• Three or more relatives with breast cancer at any age

141.
Ordering Recommendation:  

To determine if there is a heritable predisposition for breast or ovarian cancer in adults with any of the following:
• Breast cancer diagnosed at age 50 or younger
• Ovarian cancer
• Multiple primary breast cancers either in the same breast or opposite breasts
• Male breast cancer
• Triple-negative (estrogen receptor negative, progesterone receptor negative, and HER2/neu [human epidermal growth factor receptor 2] negative) breast cancer
• Pancreatic cancer with breast or ovarian cancer in the same individual or on the same side of the family
• Ashkenazi Jewish ancestry
• Two or more relatives with breast cancer, one under age 50
• Three or more relatives with breast cancer at any age

142.
Ordering Recommendation:  

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

143.
Ordering Recommendation:  

Monitor drug therapy or use when  bromide toxicity is suspected  (eg, hyperchloremia with negative anion gap and altered mental status).

144.
Ordering Recommendation:  

Identify potential bacterial cause of pneumonia.

145.
Ordering Recommendation:  

Recommended serology test to detect recent infection from Brucella in the context of a clinically compatible illness and exposure history.

146.
Ordering Recommendation:  

Identify Brucella in blood, CSF, body fluids, and abscesses.

147.
Ordering Recommendation:  

Refer to Additional Technical Information document.

148.
Ordering Recommendation:  

Preferred test for initial screening for individuals with clinical suspicion of x-linked agammaglobulinemia/hypogammaglobulinemia.

149.
Ordering Recommendation:  

• Monitor disease in patient previously diagnosed with pemphigoid and increased antibodies for IgG BP180 and/or BP230; IgG BP180 antibody levels correlate with disease activity.
• For initial diagnosis and assessment of disease progression or changes, the preferred test is the pemphigoid antibody panel (0092001); panel components include IgG and IgA epithelial BMZ antibodies and IgG bullous pemphigoid (BP180 and 230) antigens.
•To determine the involvement of IgG BMZ antibodies and pattern of reactivity on split skin substrate, order with antibody testing for IgG epithelial BMZ (0092056).
• Also, consider other types of BMZ antibody-associated disease testing, (ie, IgA epithelial BMZ (0092057), IgG collagen type VII (2010905), or herpes gestationis factor (0092283)).

150.
Ordering Recommendation:  

Monitor patient adherence.

151.
Ordering Recommendation:  

Preferred test to follow-up presumptive results. For general screening, Buprenorphine Urine Screen with Reflex to Quantitation (2012273) is preferred.

152.
153.
Ordering Recommendation:  

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out buprenorphine exposure. For follow-up testing of a presumptive result, Buprenorphine and Metabolites, Urine Quantitative (2010092) is preferred.

154.
Ordering Recommendation:  

Optimize drug therapy and monitor patient adherence.

155.
156.
Ordering Recommendation:  

Optimize drug therapy and monitor patient adherence.